MAKO Surgical Corp. is a medical device company that markets its advanced robotic solution and implants for minimally invasive orthopedic knee procedures. The RIO Robotic Arm Interactive Orthopedic System includes a platform that utilizes tactile-resistance and patient-specific visualization to prepare the knee joint for the insertion and alignment of resurfacing implants through a keyhole incision. This FDA-cleared surgeon-interactive robotic arm system allows surgeons to provide an innovative tissue-sparing bone resurfacing therapy called MAKOplasty to a large, yet underserved patient-specific population suffering from early to mid-stage osteoarthritis knee disease. MAKO has an intellectual property portfolio of more than two hundred licensed or owned patent applications relating to the areas of computer assisted surgery, haptics, robotics, and implants.