Negafile Systems was founded in Easton, PA in 1939, specializing in designing functional preservation and filing systems for photographic negatives and prints. Their signature product, the Negafile System™, featured hand-made wooden containers known for their strength, durability, and archival storage capabilities. Over time, the product line expanded to include glassine envelopes, acetate sleeves, Kraft envelopes, and numbered index tabs, catering to diverse customer uses in fields like Electron Microscopy, Stereoscopic and Lantern Slides, Laboratory glass slides, and more. Electron Microscopy Sciences acquired Negafile Systems, continuing to distribute their products and packaging solutions to the general public and industrial packaging users.